Replace Animal Tests Act of 2025

Key Points

• The bill would make it illegal for companies to submit animal testing data to major federal agencies when a scientifically valid non-animal testing method is available and accepted by that agency. This applies to the FDA, EPA, USDA, and Consumer Product Safety Commission.
• When animal testing is still necessary because no alternative exists, companies must use the fewest animals possible and minimize any pain or suffering. This codifies humane treatment standards into regulatory testing requirements.
• Federal agencies would have one year to publish guidance on which non-animal test methods they accept. They would also need to publish annual public reports detailing how many animals were used, what species, what types of testing, and how many waivers were granted.
• Companies that violate these rules face civil penalties of up to $10,000 per violation, and agencies can refuse to accept any animal testing data that was collected in violation of the law.
• Several exceptions exist: data generated before the law takes effect, data from animal tests conducted outside the U.S. to meet foreign regulatory requirements, and cases where an agency specifically requests animal testing in writing with a clear justification.